• Immunofluorescence analysis of L929 cells using SEL1L antibody (STJ113972) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using SEL1L antibody (STJ113972) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates, using SEL1L Rabbit polyclonal antibody (STJ113972) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-SEL1L antibody (22-190) (STJ113972)

SKU:
STJ113972

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SEL1L (22-190) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SEL1L
Gene ID: 6400
Uniprot ID: SE1L1_HUMAN
Immunogen Region: 22-190
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-190 of human SEL1L (NP_005056.3).
Immunogen Sequence: SSDEEGSQDESLDSKTTLTS DESVKDHTTAGRVVAGQIFL DSEESELESSIQEEEDSLKS QEGESVTEDISFLESPNPEN KDYEEPKKVRKPALTAIEGT AHGEPCHFPFLFLDKEYDEC TSDGREDGRLWCATTYDYKA DEKWGFCETEEEAAKRRQMQ EAEMMYQTG
Tissue Specificity Highly expressed in pancreas.
Post Translational Modifications N-glycosylated.
Function Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.
Protein Name Protein Sel-1 Homolog 1
Suppressor Of Lin-12-Like Protein 1
Sel-1l
Database Links Reactome: R-HSA-1912420
Reactome: R-HSA-382556
Reactome: R-HSA-5358346
Reactome: R-HSA-5362768
Reactome: R-HSA-5678895
Reactome: R-HSA-901032
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Protein Sel-1 Homolog 1 antibody
Anti-Suppressor Of Lin-12-Like Protein 1 antibody
Anti-Sel-1l antibody
Anti-SEL1L antibody
Anti-TSA305 antibody
Anti-UNQ128 antibody
Anti-PRO1063 antibody

Information sourced from Uniprot.org

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