Anti-SEC23A antibody (300-400) [S2MR] (STJ11102342)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal SEC23 (300-400) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S2MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEC23A |
| Gene ID | 10484 |
| Uniprot ID | SC23A_HUMAN |
| Immunogen Region | 300-400 |
| Immunogen Sequence | MVVGDELKTPIRSWHDIDKD NAKYVKKGTKHFEALANRAA TTGHVIDIYACALDQTGLLE MKCCPNLTGGYMVMGDSFNT SLFKQTFQRVFTKDMHGQFK M |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human Sec23AA (Q15436). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane. |
| Protein Name | Protein Transport Protein Sec23aHsec23aSec23-Related Protein A |
| Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
| Cellular Localisation | Cytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum MembraneCytoplasmCytosolEnriched At Endoplasmic Reticulum Exit SitesAlso Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec23a antibodyAnti-Hsec23a antibodyAnti-Sec23-Related Protein A antibodyAnti-SEC23A antibody |
Information sourced from Uniprot.org