• Formalin-fixed, paraffin-embedded succinate dehydrogenase deficient RCC stained with anti-SDHB antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

Anti-SDHB antibody [ZR339] (STJ180540)

SKU:
STJ180540

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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-SDHB is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZR339
Conjugation: Unconjugated
Isotype: Rabbit IgG
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: SDHB
Gene ID: 6390
Uniprot ID: SDHB_HUMAN
Specificity: Positive control: GIST
Immunogen: Synthetic peptide corresponding to residues in human SDHB was used as an immunogen
Function Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Protein Name Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - Mitochondrial
Iron-Sulfur Subunit Of Complex Ii
Ip
Database Links Reactome: R-HSA-611105
Reactome: R-HSA-71403
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Matrix Side
Alternative Antibody Names Anti-Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - Mitochondrial antibody
Anti-Iron-Sulfur Subunit Of Complex Ii antibody
Anti-Ip antibody
Anti-SDHB antibody
Anti-SDH antibody
Anti-SDH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance