• Western blot analysis of lysates from mouse liver, using HCC1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HCC1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-SARNP antibody (147-196 aa) (STJ92295)

SKU:
STJ92295

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SAP domain-containing ribonucleoprotein (147-196 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SARNP
Gene ID: 84324
Uniprot ID: SARNP_HUMAN
Immunogen Region: 147-196 aa
Specificity: CIP29 Polyclonal Antibody detects endogenous levels of CIP29 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HCC1 at the amino acid range 147-196
Function Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Protein Name Sap Domain-Containing Ribonucleoprotein
Cytokine-Induced Protein Of 29 Kda
Nuclear Protein Hcc-1
Proliferation-Associated Cytokine-Inducible Protein Cip29
Database Links Reactome: R-HSA-159236
Reactome: R-HSA-72187
Reactome: R-HSA-73856
Cellular Localisation Nucleus
Nucleus Speckle
Alternative Antibody Names Anti-Sap Domain-Containing Ribonucleoprotein antibody
Anti-Cytokine-Induced Protein Of 29 Kda antibody
Anti-Nuclear Protein Hcc-1 antibody
Anti-Proliferation-Associated Cytokine-Inducible Protein Cip29 antibody
Anti-SARNP antibody
Anti-HCC1 antibody
Anti-HSPC316 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance