| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SAP130 (819-1048) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SAP130 |
| Gene ID: |
79595 |
| Uniprot ID: |
SP130_HUMAN |
| Immunogen Region: |
819-1048 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2). |
| Immunogen Sequence: |
LSMPTSDLPPGASPRKKPRK QQHVISTEEGDMMETNSTDD EKSTAKSLLVKAEKRKSPPK EYIDEEGVRYVPVRPRPPIT LLRHYRNPWKAAYHHFQRYS DVRVKEEKKAMLQEIANQKG VSCRAQGWKVHLCAAQLLQL TNLEHDVYERLTNLQEGIIP KKKAATDDDLHRINELIQGN MQRCKLVMDQISEARDSMLK VLDHKDRVLKLLNKNGTVKK VSKLKRKEKV |
| Tissue Specificity | Expressed in various cancer cell ines. |
| Post Translational Modifications | Acetylated. Sumoylated with SUMO1. |
| Function | Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. |
| Protein Name | Histone Deacetylase Complex Subunit Sap130130 Kda Sin3-Associated PolypeptideSin3-Associated Polypeptide P130 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-427413 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase Complex Subunit Sap130 antibodyAnti-130 Kda Sin3-Associated Polypeptide antibodyAnti-Sin3-Associated Polypeptide P130 antibodyAnti-SAP130 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
