| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SAP130 |
| Gene ID: | 79595 |
| Uniprot ID: | SP130_HUMAN |
| Immunogen Region: | 819-1048 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2). |
| Immunogen Sequence: | LSMPTSDLPPGASPRKKPRK QQHVISTEEGDMMETNSTDD EKSTAKSLLVKAEKRKSPPK EYIDEEGVRYVPVRPRPPIT LLRHYRNPWKAAYHHFQRYS DVRVKEEKKAMLQEIANQKG VSCRAQGWKVHLCAAQLLQL TNLEHDVYERLTNLQEGIIP KKKAATDDDLHRINELIQGN MQRCKLVMDQISEARDSMLK VLDHKDRVLKLLNKNGTVKK VSKLKRKEKV |
| Tissue Specificity | Expressed in various cancer cell ines. |
| Post Translational Modifications | Acetylated. Sumoylated with SUMO1. |
| Function | Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. |
| Protein Name | Histone Deacetylase Complex Subunit Sap130130 Kda Sin3-Associated PolypeptideSin3-Associated Polypeptide P130 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-427413 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase Complex Subunit Sap130 antibodyAnti-130 Kda Sin3-Associated Polypeptide antibodyAnti-Sin3-Associated Polypeptide P130 antibodyAnti-SAP130 antibody |
Information sourced from Uniprot.org
