Anti-SAMSN1 antibody (316-366 aa) (STJ195571)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SAMN1 at the amino acid range 316-366
General Information
| Short Description | Rabbit polyclonal anti-SAM domain-containing protein SAMSN-1 (316-366 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SAMSN1 |
| Gene ID | 64092 |
| Uniprot ID | SAMN1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SAMN1 at the amino acid range 316-366 |
| Immunogen Region | 316-366 aa |
| Specificity | This antibody detects endogenous levels of SAMN1 at Human/Mouse |
Additional Info
| Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. |
| Protein Name | Sam Domain-Containing Protein Samsn-1Hematopoietic Adaptor Containing Sh3 And Sam Domains 1Nash1Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1Sh3-Sam Adaptor Protein |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCell ProjectionRuffleShuttles Between Cytoplasm And NucleusColocalizes With The Actin Cytoskeleton And Actin-Rich Membrane Ruffles |
| Alternative Antibody Names | Anti-Sam Domain-Containing Protein Samsn-1 antibodyAnti-Hematopoietic Adaptor Containing Sh3 And Sam Domains 1 antibodyAnti-Nash1 antibodyAnti-Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1 antibodyAnti-Sh3-Sam Adaptor Protein antibodyAnti-SAMSN1 antibodyAnti-HACS1 antibody |
Information sourced from Uniprot.org