| Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. |
| Protein Name | Sam Domain-Containing Protein Samsn-1Hematopoietic Adaptor Containing Sh3 And Sam Domains 1Nash1Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1Sh3-Sam Adaptor Protein |
| Cellular Localisation | NucleusCytoplasmCell ProjectionRuffleShuttles Between Cytoplasm And NucleusColocalizes With The Actin Cytoskeleton And Actin-Rich Membrane Ruffles |
| Alternative Antibody Names | Anti-Sam Domain-Containing Protein Samsn-1 antibodyAnti-Hematopoietic Adaptor Containing Sh3 And Sam Domains 1 antibodyAnti-Nash1 antibodyAnti-Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1 antibodyAnti-Sh3-Sam Adaptor Protein antibodyAnti-SAMSN1 antibodyAnti-HACS1 antibody |
Information sourced from Uniprot.org