Anti-SAMM50 antibody (1-220) (STJ25440)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SAMM50 (1-220) antibody for use in WB, IHC-P, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SAMM50 |
| Gene ID | 25813 |
| Uniprot ID | SAM50_HUMAN |
| Immunogen Region | 1-220 |
| Immunogen Sequence | MGTVHARSLEPLPSSGPDFG GLGEEAEFVEVEPEAKQEIL ENKDVVVQHVHFDGLGRTKD DIIICEIGDVFKAKNLIEVM RKSHEAREKLLRLGIFRQVD VLIDTCQGDDALPNGLDVTF EVTELRRLTGSYNTMVGNNE GSMVLGLKLPNLLGRAEKVT FQFSYGTKETSYGLSFFKPR PGNFERNFSVNLYKVTGQFP WSSLRETDRGMSAEYSFPIW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SAMM50 (NP_056195.3). |
Additional Info
| Function | Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex. |
| Protein Name | Sorting And Assembly Machinery Component 50 HomologTransformation-Related Gene 3 ProteinTrg-3 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8949613Reactome: R-HSA-9013404 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane ProteinCytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Sorting And Assembly Machinery Component 50 Homolog antibodyAnti-Transformation-Related Gene 3 Protein antibodyAnti-Trg-3 antibodyAnti-SAMM50 antibodyAnti-SAM50 antibodyAnti-CGI-51 antibodyAnti-TRG3 antibody |
Information sourced from Uniprot.org