Anti-SALL4 antibody (853-1053) (STJ118633)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SALL4 (853-1053) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SALL4 |
| Gene ID | 57167 |
| Uniprot ID | SALL4_HUMAN |
| Immunogen Region | 853-1053 |
| Immunogen Sequence | PGMTPLLAAQPRRQAKQHGC TRCGKNFSSASALQIHERTH TGEKPFVCNICGRAFTTKGN LKVHYMTHGANNNSARRGRK LAIENTMALLGTDGKRVSEI FPKEILAPSVNVDPVVWNQY TSMLNGGLAVKTNEISVIQS GGVPTLPVSLGATSVVNNAT VSKMDGSQSGISADVEKPSA TDGVPKHQFPHFLEENKIAV S |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 853-1053 of human Sall4 (NP_065169.1). |
Additional Info
| Tissue Specificity | Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML). |
| Post Translational Modifications | Isoform SALL4B exists primarily as a ubiquitinated form. Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. |
| Function | Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. |
| Protein Name | Sal-Like Protein 4Zinc Finger Protein 797Zinc Finger Protein Sall4 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723Reactome: R-HSA-8943724 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Sal-Like Protein 4 antibodyAnti-Zinc Finger Protein 797 antibodyAnti-Zinc Finger Protein Sall4 antibodyAnti-SALL4 antibodyAnti-ZNF797 antibody |
Information sourced from Uniprot.org