Anti-S100P antibody (C-Term) [ZR115] (STJ180596)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant fragment corresponding to C-terminal of human S100P protein
General Information
| Short Description | Rabbit monoclonal S100P (C-Term) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR115 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | S100P |
| Gene ID | 6286 |
| Uniprot ID | S100P_HUMAN |
| Immunogen | Recombinant fragment corresponding to C-terminal of human S100P protein |
| Immunogen Region | C-Term |
| Specificity | Positive Control: Colon cancer |
Additional Info
| Tissue Specificity | Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. |
| Function | May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). |
| Protein Name | Protein S100-PMigration-Inducing Gene 9 ProteinMig9Protein S100-ES100 Calcium-Binding Protein P |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionMicrovillus MembraneColocalizes With S100pbp In The NucleusColocalizes With Ezr In The Microvilli In A Calcium-Dependent Manner |
| Alternative Antibody Names | Anti-Protein S100-P antibodyAnti-Migration-Inducing Gene 9 Protein antibodyAnti-Mig9 antibodyAnti-Protein S100-E antibodyAnti-S100 Calcium-Binding Protein P antibodyAnti-S100P antibodyAnti-S100E antibody |
Information sourced from Uniprot.org