| Host: |
Rabbit |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-S100P (C-Term) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ZR115 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: |
Affinity purified |
| Dilution Range: |
1:100-200 |
| Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: |
S100P |
| Gene ID: |
6286 |
| Uniprot ID: |
S100P_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
Positive Control: Colon cancer |
| Immunogen: |
Recombinant fragment corresponding to C-terminal of human S100P protein |
| Tissue Specificity | Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. |
| Function | May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). |
| Protein Name | Protein S100-PMigration-Inducing Gene 9 ProteinMig9Protein S100-ES100 Calcium-Binding Protein P |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionMicrovillus MembraneColocalizes With S100pbp In The NucleusColocolizes With Ezr In The Microvilli In A Calcium-Dependent Manner |
| Alternative Antibody Names | Anti-Protein S100-P antibodyAnti-Migration-Inducing Gene 9 Protein antibodyAnti-Mig9 antibodyAnti-Protein S100-E antibodyAnti-S100 Calcium-Binding Protein P antibodyAnti-S100P antibodyAnti-S100E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
