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Anti-S100A1 antibody (10-59 aa) (STJ95562)

Western blot analysis of lysates from A549 cells, using S100 A1 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of A549 cells, using S100 A1 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using S100 A1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of various cells using S-100 Alpha Polyclonal Antibody

Anti-S100A1 antibody (10-59 aa) (STJ95562)

SKU:

STJ95562

$62.10 - $305.10

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Protein S100-A1 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	S100A1
Gene ID:	6271
Uniprot ID:	S10A1_HUMAN
Immunogen Region:	10-59 aa
Specificity:	S-100 Alpha Polyclonal Antibody detects endogenous levels of S-100 Alpha protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human S100 A1 at the amino acid range 10-59

Post Translational Modifications	Glutathionylated.glutathionylation increases affinity to calcium about 10-fold.
Function	Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes. These changes allow interactions with specific target proteins and modulate their activity. Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca(2+)-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole.
Protein Name	Protein S100-A1 S-100 Protein Alpha Chain S-100 Protein Subunit Alpha S100 Calcium-Binding Protein A1
Database Links	Reactome: R-HSA-1236974 Reactome: R-HSA-166058 Reactome: R-HSA-5602498 Reactome: R-HSA-5603041 Reactome: R-HSA-5686938
Cellular Localisation	Cytoplasm Sarcoplasmic Reticulum Mitochondrion
Alternative Antibody Names	Anti-Protein S100-A1 antibody Anti-S-100 Protein Alpha Chain antibody Anti-S-100 Protein Subunit Alpha antibody Anti-S100 Calcium-Binding Protein A1 antibody Anti-S100A1 antibody Anti-S100A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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