Anti-RXRG antibody (Hinge region) [1373] (STJA0003769)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenSynthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH.
General Information
| Short Description | Mouse monoclonal anti-RXRG (Hinge region) for use in WB in Human, Rat, Bovine, Mouse and Non-Human Primates samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Rat/Bovine/Mouse/Non-Human Primates |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1373 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | This antibody was protein g purified culture from supernatant. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RXRG |
| Gene ID | 6258 |
| Uniprot ID | RXRG_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH. |
| Immunogen Region | Hinge region |
Additional Info
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
| Post Translational Modifications | Acetylated by EP300. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. |
| Protein Name | Retinoic Acid Receptor Rxr-GammaNuclear Receptor Subfamily 2 Group B Member 3Retinoid X Receptor Gamma |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Gamma antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 3 antibodyAnti-Retinoid X Receptor Gamma antibodyAnti-RXRG antibodyAnti-NR2B3 antibody |
Information sourced from Uniprot.org