| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Bovine/Mouse/Non-Human Primates |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-RXRG (Hinge region) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
1373 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: |
This antibody was protein g purified culture from supernatant. |
| Dilution Range: |
WB 1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RXRG |
| Gene ID: |
6258 |
| Uniprot ID: |
RXRG_HUMAN |
| Immunogen Region: |
Hinge region |
| Immunogen: |
Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH. |
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
| Post Translational Modifications | Acetylated by EP300. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. |
| Protein Name | Retinoic Acid Receptor Rxr-GammaNuclear Receptor Subfamily 2 Group B Member 3Retinoid X Receptor Gamma |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Gamma antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 3 antibodyAnti-Retinoid X Receptor Gamma antibodyAnti-RXRG antibodyAnti-NR2B3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
