| Tissue Specificity | Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver.low levels in brain, kidney, and pancreas. |
| Post Translational Modifications | May be post-translationally modified by both palmitoylation and polyisoprenylation. Fatty-acylation at Lys-192, Lys-194.lys-196 and Lys-197 is required for localization to the plasma membrane and activity. Defatty-acylated by SIRT6, affecting its localization to the plasma membrane. |
| Function | GTP-binding protein with GTPase activity involved in the regulation of MAPK signaling pathway, thereby controlling multiple cellular processes. Involved in the regulation of MAPK signaling pathway. Regulation of craniofacial development. |
| Protein Name | Ras-Related Protein R-Ras2Ras-Like Protein Tc21Teratocarcinoma Oncogene |
| Database Links | Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Ras-Related Protein R-Ras2 antibodyAnti-Ras-Like Protein Tc21 antibodyAnti-Teratocarcinoma Oncogene antibodyAnti-RRAS2 antibodyAnti-TC21 antibody |
Information sourced from Uniprot.org
