Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RPS6KA6 (646-745) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RPS6KA6 |
Gene ID: |
27330 |
Uniprot ID: |
KS6A6_HUMAN |
Immunogen Region: |
646-745 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 646-745 of human RPS6KA6 (NP_055311.1). |
Immunogen Sequence: |
GGNWDNISDGAKDLLSHMLH MDPHQRYTAEQILKHSWITH RDQLPNDQPKRNDVSHVVKG AMVATYSALTHKTFQPVLEP VAASSLAQRRSMKKRTSTGL |
Post Translational Modifications | Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells. |
Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. |
Protein Name | Ribosomal Protein S6 Kinase Alpha-6S6k-Alpha-690 Kda Ribosomal Protein S6 Kinase 6P90-Rsk 6P90rsk6Ribosomal S6 Kinase 4Rsk-4Pp90rsk4 |
Database Links | Reactome: R-HSA-437239Reactome: R-HSA-442742Reactome: R-HSA-444257 |
Cellular Localisation | CytoplasmCytosolNucleusPredominantly Cytosolic |
Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Alpha-6 antibodyAnti-S6k-Alpha-6 antibodyAnti-90 Kda Ribosomal Protein S6 Kinase 6 antibodyAnti-P90-Rsk 6 antibodyAnti-P90rsk6 antibodyAnti-Ribosomal S6 Kinase 4 antibodyAnti-Rsk-4 antibodyAnti-Pp90rsk4 antibodyAnti-RPS6KA6 antibodyAnti-RSK4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance