Anti-RPS6KA6 antibody (646-745) (STJ117076)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RPS6KA6 (646-745) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPS6KA6 |
| Gene ID | 27330 |
| Uniprot ID | KS6A6_HUMAN |
| Immunogen Region | 646-745 |
| Immunogen Sequence | GGNWDNISDGAKDLLSHMLH MDPHQRYTAEQILKHSWITH RDQLPNDQPKRNDVSHVVKG AMVATYSALTHKTFQPVLEP VAASSLAQRRSMKKRTSTGL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 646-745 of human RPS6KA6 (NP_055311.1). |
Additional Info
| Post Translational Modifications | Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells. |
| Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. |
| Protein Name | Ribosomal Protein S6 Kinase Alpha-6S6k-Alpha-690 Kda Ribosomal Protein S6 Kinase 6P90-Rsk 6P90rsk6Ribosomal S6 Kinase 4Rsk-4Pp90rsk4 |
| Database Links | Reactome: R-HSA-437239Reactome: R-HSA-442742Reactome: R-HSA-444257 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Cytosolic |
| Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Alpha-6 antibodyAnti-S6k-Alpha-6 antibodyAnti-90 Kda Ribosomal Protein S6 Kinase 6 antibodyAnti-P90-Rsk 6 antibodyAnti-P90rsk6 antibodyAnti-Ribosomal S6 Kinase 4 antibodyAnti-Rsk-4 antibodyAnti-Pp90rsk4 antibodyAnti-RPS6KA6 antibodyAnti-RSK4 antibody |
Information sourced from Uniprot.org