Anti-RPL23A antibody (17-67) (STJA0006334)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RL23A AA range: 17-67
General Information
| Short Description | Rabbit polyclonal anti-Large ribosomal subunit protein uL23 (17-67) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPL23A |
| Gene ID | 6147 |
| Uniprot ID | RL23A_HUMAN |
| Immunogen | Synthesized peptide derived from human RL23A AA range: 17-67 |
| Immunogen Region | 17-67 |
| Specificity | This antibody detects endogenous levels of human RL23A |
Additional Info
| Function | Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination. |
| Protein Name | Large Ribosomal Subunit Protein Ul2360s Ribosomal Protein L23a |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72689Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | CytoplasmNucleusAlthough Rpl23a Is Functional Within The CytoplasmThe Assembly Of Ribosomal Subunits Occurs In The NucleusRpl23a Nuclear Import Is Mediated By Ipo5/Ranbp5Ipo7/Ranbp7Kpnb1/Importin-Beta Or Tpno1/Trn |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ul23 antibodyAnti-60s Ribosomal Protein L23a antibodyAnti-RPL23A antibody |
Information sourced from Uniprot.org