Anti-RPL23A antibody (17-67) (STJA0006334)

SKU:
STJA0006334

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Large ribosomal subunit protein uL23 (17-67) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RPL23A
Gene ID: 6147
Uniprot ID: RL23A_HUMAN
Immunogen Region: 17-67
Specificity: This antibody detects endogenous levels of human RL23A
Immunogen: Synthesized peptide derived from human RL23A AA range: 17-67
Function Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.
Protein Name Large Ribosomal Subunit Protein Ul23
60s Ribosomal Protein L23a
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-156902
Reactome: R-HSA-1799339
Reactome: R-HSA-192823
Reactome: R-HSA-2408557
Reactome: R-HSA-6791226
Reactome: R-HSA-72689
Reactome: R-HSA-72706
Reactome: R-HSA-72764
Reactome: R-HSA-9010553
Reactome: R-HSA-9633012
Reactome: R-HSA-975956
Reactome: R-HSA-975957
Cellular Localisation Cytoplasm
Nucleus
Although Rpl23a Is Functional Within The Cytoplasm
The Assembly Of Ribosomal Subunits Occurs In The Nucleus
Rpl23a Nuclear Import Is Mediated By Ipo5/Ranbp5
Ipo7/Ranbp7
Kpnb1/Importin-Beta Or Tpno1/Trn
Alternative Antibody Names Anti-Large Ribosomal Subunit Protein Ul23 antibody
Anti-60s Ribosomal Protein L23a antibody
Anti-RPL23A antibody

Information sourced from Uniprot.org

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