Anti-RNLS antibody (STJA0007184)

SKU:
STJA0007184

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Renalase is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RNLS
Gene ID: 55328
Uniprot ID: RNLS_HUMAN
Specificity: This antibody detects endogenous levels of RENALASE at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human RENALASE
Function Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Protein Name Renalase
Monoamine Oxidase-C
Mao-C
Database Links Reactome: R-HSA-197264
Cellular Localisation Secreted
Alternative Antibody Names Anti-Renalase antibody
Anti-Monoamine Oxidase-C antibody
Anti-Mao-C antibody
Anti-RNLS antibody
Anti-C10orf59 antibody

Information sourced from Uniprot.org

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