| Short Description : | Rabbit polyclonal RNASE2 (28-161) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RNASE2 |
| Gene ID: | 6036 |
| Uniprot ID: | RNAS2_HUMAN |
| Immunogen Region: | 28-161 |
| Immunogen Sequence: | KPPQFTWAQWFETQHINMTS QQCTNAMQVINNYQRRCKNQ NTFLLTTFANVVNVCGNPNM TCPSNKTRKNCHHSGSQVPL IHCNLTTPSPQNISNCRYAQ TPANMFYIVACDNRDQRRDP PQYPVVPVHLDRII |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-161 of human RNASE2 (NP_002925.1). |
| Tissue Specificity | Liver, lung, spleen, leukocytes and body fluids. |
| Post Translational Modifications | A particular signal processing and glycosylation pattern may differentiate the UpI2 RNase, found specifically in pregnant women urine, from other nonsecretory RNases. |
| Function | This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. |
| Protein Name | Non-Secretory RibonucleaseEosinophil-Derived NeurotoxinRnase Upi-2Ribonuclease 2Rnase 2Ribonuclease Us |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | LysosomeCytoplasmic GranuleMatrix Of Eosinophil's Large Specific Granule |
| Alternative Antibody Names | Anti-Non-Secretory Ribonuclease antibodyAnti-Eosinophil-Derived Neurotoxin antibodyAnti-Rnase Upi-2 antibodyAnti-Ribonuclease 2 antibodyAnti-Rnase 2 antibodyAnti-Ribonuclease Us antibodyAnti-RNASE2 antibodyAnti-EDN antibodyAnti-RNS2 antibody |
Information sourced from Uniprot.org
