| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Regulating synaptic membrane exocytosis protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RIMS1 |
| Gene ID: |
22999 |
| Uniprot ID: |
RIMS1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RIM1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human RIM1 |
| Post Translational Modifications | Phosphorylated by BRSK1. |
| Function | Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Regulating Synaptic Membrane Exocytosis Protein 1Rab-3-Interacting Molecule 1Rim 1Rab-3-Interacting Protein 2 |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-181430Reactome: R-HSA-210500Reactome: R-HSA-212676Reactome: R-HSA-264642Reactome: R-HSA-888590 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapsePresynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Regulating Synaptic Membrane Exocytosis Protein 1 antibodyAnti-Rab-3-Interacting Molecule 1 antibodyAnti-Rim 1 antibodyAnti-Rab-3-Interacting Protein 2 antibodyAnti-RIMS1 antibodyAnti-KIAA0340 antibodyAnti-RAB3IP2 antibodyAnti-RIM1 antibodyAnti-Nbla00761 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
