Anti-RIMS1 antibody (STJA0007382)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RIM1
General Information
| Short Description | Rabbit polyclonal anti-Regulating synaptic membrane exocytosis protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RIMS1 |
| Gene ID | 22999 |
| Uniprot ID | RIMS1_HUMAN |
| Immunogen | Synthesized peptide derived from human RIM1 |
| Specificity | This antibody detects endogenous levels of RIM1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated by BRSK1. |
| Function | Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Regulating Synaptic Membrane Exocytosis Protein 1Rab-3-Interacting Molecule 1Rim 1Rab-3-Interacting Protein 2 |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-181430Reactome: R-HSA-210500Reactome: R-HSA-212676Reactome: R-HSA-264642Reactome: R-HSA-888590 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSynapsePresynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Regulating Synaptic Membrane Exocytosis Protein 1 antibodyAnti-Rab-3-Interacting Molecule 1 antibodyAnti-Rim 1 antibodyAnti-Rab-3-Interacting Protein 2 antibodyAnti-RIMS1 antibodyAnti-KIAA0340 antibodyAnti-RAB3IP2 antibodyAnti-RIM1 antibodyAnti-Nbla00761 antibody |
Information sourced from Uniprot.org