| Short Description : | Rabbit polyclonal anti-RGS19 for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. Use at a dilution of 1:1000 to 1: 3000. The optimal dilution should be determined by the end user. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | RGS19 |
| Gene ID: | 10287 |
| Uniprot ID: | RGS19_HUMAN |
| Immunogen: | A synthetic peptide from human RGS19 conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in rat and mouse. |
| Specificity: | Specific for RGS19. |
| Post Translational Modifications | Fatty acylated. Heavily palmitoylated in the cysteine string motif. Phosphorylated, mainly on serine residues. |
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. |
| Protein Name | Regulator Of G-Protein Signaling 19Rgs19G-Alpha-Interacting ProteinGaip |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-418597 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 19 antibodyAnti-Rgs19 antibodyAnti-G-Alpha-Interacting Protein antibodyAnti-Gaip antibodyAnti-RGS19 antibodyAnti-GAIP antibodyAnti-GNAI3IP antibody |
Information sourced from Uniprot.org
