Anti-RGS12 antibody (141-190 aa) (STJ95437)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RGS12 at the amino acid range 141-190
General Information
| Short Description | Rabbit polyclonal anti-Regulator of G-protein signaling 12 (141-190 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RGS12 |
| Gene ID | 6002 |
| Uniprot ID | RGS12_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RGS12 at the amino acid range 141-190 |
| Immunogen Region | 141-190 aa |
| Specificity | RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein. |
Additional Info
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Isoform 5: Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis. |
| Protein Name | Regulator Of G-Protein Signaling 12Rgs12 |
| Database Links | Reactome: R-HSA-418594 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionDendriteSynapseIsoform 5: Nucleus MatrixAlso Localized To Discrete Nuclear Foci That Are Distinct From Sites Of Rna ProcessingPml Nuclear BodiesAnd Pcg Domains |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 12 antibodyAnti-Rgs12 antibodyAnti-RGS12 antibody |
Information sourced from Uniprot.org