Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Regulator of G-protein signaling 12 (141-190 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RGS12 |
Gene ID: |
6002 |
Uniprot ID: |
RGS12_HUMAN |
Immunogen Region: |
141-190 aa |
Specificity: |
RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human RGS12 at the amino acid range 141-190 |
Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Isoform 5: Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis. |
Protein Name | Regulator Of G-Protein Signaling 12Rgs12 |
Database Links | Reactome: R-HSA-418594 |
Cellular Localisation | NucleusCytoplasmCell ProjectionDendriteSynapseIsoform 5: Nucleus MatrixAlso Localized To Discrete Nuclear Foci That Are Distinct From Sites Of Rna ProcessingPml Nuclear BodiesAnd Pcg Domains |
Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 12 antibodyAnti-Rgs12 antibodyAnti-RGS12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance