• Western blot analysis of RGS12 Antibody. The lane on the right is blocked with the RGS12 peptide.
  • Western blot analysis of the lysates from HUVECcells using RGS12 antibody.
  • Western blot analysis of 3T3 cells using RGS12 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-RGS12 antibody (141-190 aa) (STJ95437)

SKU:
STJ95437

Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Regulator of G-protein signaling 12 (141-190 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RGS12
Gene ID: 6002
Uniprot ID: RGS12_HUMAN
Immunogen Region: 141-190 aa
Specificity: RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RGS12 at the amino acid range 141-190
Function Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Isoform 5: Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.
Protein Name Regulator Of G-Protein Signaling 12
Rgs12
Database Links Reactome: R-HSA-418594
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Dendrite
Synapse
Isoform 5: Nucleus Matrix
Also Localized To Discrete Nuclear Foci That Are Distinct From Sites Of Rna Processing
Pml Nuclear Bodies
And Pcg Domains
Alternative Antibody Names Anti-Regulator Of G-Protein Signaling 12 antibody
Anti-Rgs12 antibody
Anti-RGS12 antibody

Information sourced from Uniprot.org

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