Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | RFX2 |
Gene ID: | 5990 |
Uniprot ID: | RFX2_HUMAN |
Immunogen Region: | 295-450 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2). |
Immunogen Sequence: | MHQKPRYRPAQKTDSLGDSG SHSGLHSTPEQTMAVQSQHH QQYIDVSHVFPEFPAPDLGS FLLQDGVTLHDVKALQLVYR RHCEATVDVVMNLQFHYIEK LWLSFWNSKASSSDGPTSLP ASDEDPEGAVLPKDKLISLC QCDPILRWMRSCDHIL |
Function | Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6. |
Protein Name | Dna-Binding Protein Rfx2Regulatory Factor X 2 |
Cellular Localisation | NucleusCytoplasmMainly Expressed In The Nucleus And At Lower Level In Cytoplasm |
Alternative Antibody Names | Anti-Dna-Binding Protein Rfx2 antibodyAnti-Regulatory Factor X 2 antibodyAnti-RFX2 antibody |
Information sourced from Uniprot.org