Anti-RFX2 antibody (295-450) (STJ119618)

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STJ119618
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RFX2
Gene ID: 5990
Uniprot ID: RFX2_HUMAN
Immunogen Region: 295-450
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2).
Immunogen Sequence: MHQKPRYRPAQKTDSLGDSG SHSGLHSTPEQTMAVQSQHH QQYIDVSHVFPEFPAPDLGS FLLQDGVTLHDVKALQLVYR RHCEATVDVVMNLQFHYIEK LWLSFWNSKASSSDGPTSLP ASDEDPEGAVLPKDKLISLC QCDPILRWMRSCDHIL
Function Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6.
Protein Name Dna-Binding Protein Rfx2
Regulatory Factor X 2
Cellular Localisation Nucleus
Cytoplasm
Mainly Expressed In The Nucleus And At Lower Level In Cytoplasm
Alternative Antibody Names Anti-Dna-Binding Protein Rfx2 antibody
Anti-Regulatory Factor X 2 antibody
Anti-RFX2 antibody

Information sourced from Uniprot.org