| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RFX2 (295-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RFX2 |
| Gene ID: |
5990 |
| Uniprot ID: |
RFX2_HUMAN |
| Immunogen Region: |
295-450 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2). |
| Immunogen Sequence: |
MHQKPRYRPAQKTDSLGDSG SHSGLHSTPEQTMAVQSQHH QQYIDVSHVFPEFPAPDLGS FLLQDGVTLHDVKALQLVYR RHCEATVDVVMNLQFHYIEK LWLSFWNSKASSSDGPTSLP ASDEDPEGAVLPKDKLISLC QCDPILRWMRSCDHIL |
| Function | Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6. |
| Protein Name | Dna-Binding Protein Rfx2Regulatory Factor X 2 |
| Cellular Localisation | NucleusCytoplasmMainly Expressed In The Nucleus And At Lower Level In Cytoplasm |
| Alternative Antibody Names | Anti-Dna-Binding Protein Rfx2 antibodyAnti-Regulatory Factor X 2 antibodyAnti-RFX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
