Anti-RFC4 antibody (204-363) (STJ27438)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RFC4 (204-363) antibody for use in WB, IF, ICC, IP and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RFC4 |
| Gene ID | 5984 |
| Uniprot ID | RFC4_HUMAN |
| Immunogen Region | 204-363 |
| Immunogen Sequence | DKIQQQRLLDIAKKENVKIS DEGIAYLVKVSEGDLRKAIT FLQSATRLTGGKEITEKVIT DIAGVIPAEKIDGVFAACQS GSFDKLEAVVKDLIDEGHAA TQLVNQLHDVVVENNLSDKQ KSIITEKLAEVDKCLADGAD EHLQLISLCATVMQQLSQNC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1). |
Additional Info
| Function | Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. The RFC4 subunit probably functions as a scaffold on which the other complex components can assemble. |
| Protein Name | Replication Factor C Subunit 4Activator 1 37 Kda SubunitA1 37 Kda SubunitActivator 1 Subunit 4Replication Factor C 37 Kda SubunitRf-C 37 Kda SubunitRfc37 |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-110314Reactome: R-HSA-110320Reactome: R-HSA-174411Reactome: R-HSA-176187Reactome: R-HSA-5651801Reactome: R-HSA-5655862Reactome: R-HSA-5656121Reactome: R-HSA-5656169Reactome: R-HSA-5685938Reactome: R-HSA-5685942Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-5696397Reactome: R-HSA-5696400Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6804756Reactome: R-HSA-69091Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Replication Factor C Subunit 4 antibodyAnti-Activator 1 37 Kda Subunit antibodyAnti-A1 37 Kda Subunit antibodyAnti-Activator 1 Subunit 4 antibodyAnti-Replication Factor C 37 Kda Subunit antibodyAnti-Rf-C 37 Kda Subunit antibodyAnti-Rfc37 antibodyAnti-RFC4 antibody |
Information sourced from Uniprot.org