| Host: | Rabbit |
| Applications: | WB/IF/ICC/IP/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RFC4 |
| Gene ID: | 5984 |
| Uniprot ID: | RFC4_HUMAN |
| Immunogen Region: | 204-363 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1). |
| Immunogen Sequence: | DKIQQQRLLDIAKKENVKIS DEGIAYLVKVSEGDLRKAIT FLQSATRLTGGKEITEKVIT DIAGVIPAEKIDGVFAACQS GSFDKLEAVVKDLIDEGHAA TQLVNQLHDVVVENNLSDKQ KSIITEKLAEVDKCLADGAD EHLQLISLCATVMQQLSQNC |
| Function | Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. The RFC4 subunit probably functions as a scaffold on which the other complex components can assemble. |
| Protein Name | Replication Factor C Subunit 4Activator 1 37 Kda SubunitA1 37 Kda SubunitActivator 1 Subunit 4Replication Factor C 37 Kda SubunitRf-C 37 Kda SubunitRfc37 |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-110314Reactome: R-HSA-110320Reactome: R-HSA-174411Reactome: R-HSA-176187Reactome: R-HSA-5651801Reactome: R-HSA-5655862Reactome: R-HSA-5656121Reactome: R-HSA-5656169Reactome: R-HSA-5685938Reactome: R-HSA-5685942Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-5696397Reactome: R-HSA-5696400Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6804756Reactome: R-HSA-69091Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Replication Factor C Subunit 4 antibodyAnti-Activator 1 37 Kda Subunit antibodyAnti-A1 37 Kda Subunit antibodyAnti-Activator 1 Subunit 4 antibodyAnti-Replication Factor C 37 Kda Subunit antibodyAnti-Rf-C 37 Kda Subunit antibodyAnti-Rfc37 antibodyAnti-RFC4 antibody |
Information sourced from Uniprot.org
