![Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180565/404343/STJA0010670_7__62712.1738951567.jpg?c=1 "Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)")
![Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180565/404343/STJA0010670_7__62712.1738951567.jpg?c=1 "Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)")
Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein corresponding to Mouse S100A4
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-S100A4 for use in WB, IHC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SR0670 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB (H, M, R) 1:500-1:2000IHC/IF (H, M, R) 1:800-1:1600 |
| Formulation | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | S100A4 |
| Gene ID | 6275 |
| Uniprot ID | S10A4_HUMAN |
| Immunogen | Recombinant protein corresponding to Mouse S100A4 |
Additional Info
| Function | Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors. |
| Protein Name | Protein S100-A4CalvasculinMetastasinPlacental Calcium-Binding ProteinProtein Mts1S100 Calcium-Binding Protein A4 |
| Database Links | |
| Cellular Localisation | SecretedNucleusCytoplasm |
| Alternative Antibody Names | Anti-Protein S100-A4 antibodyAnti-Calvasculin antibodyAnti-Metastasin antibodyAnti-Placental Calcium-Binding Protein antibodyAnti-Protein Mts1 antibodyAnti-S100 Calcium-Binding Protein A4 antibodyAnti-S100A4 antibodyAnti-CAPL antibodyAnti-MTS1 antibody |
Information sourced from Uniprot.org