Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)

Anti-Recombinant-S100A4 antibody [SR0670] (STJA0010670)

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STJA0010670
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Short Description :Rabbit monoclonal anti-Recombinant-S100A4 for use in WB, IHC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SR0670
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity purification
Dilution Range:WB (H, M, R) 1:500-1:2000
IHC/IF (H, M, R) 1:800-1:1600
Formulation:PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol.
Storage Instruction:Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.
Gene Symbol:S100A4
Gene ID:6275
Uniprot ID:S10A4_HUMAN
Immunogen:Recombinant protein corresponding to Mouse S100A4
Function Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors.
Protein Name Protein S100-A4
Calvasculin
Metastasin
Placental Calcium-Binding Protein
Protein Mts1
S100 Calcium-Binding Protein A4
Database Links
Cellular Localisation Secreted
Nucleus
Cytoplasm
Alternative Antibody Names Anti-Protein S100-A4 antibody
Anti-Calvasculin antibody
Anti-Metastasin antibody
Anti-Placental Calcium-Binding Protein antibody
Anti-Protein Mts1 antibody
Anti-S100 Calcium-Binding Protein A4 antibody
Anti-S100A4 antibody
Anti-CAPL antibody
Anti-MTS1 antibody

Information sourced from Uniprot.org

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