Anti-Recombinant-MMP17 antibody [RM2K90] (STJA0025955)

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STJA0025955
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IF/IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Matrix Metalloproteinase-17 is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2K90
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: MMP17
Gene ID: 4326
Uniprot ID: MMP17_HUMAN
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Protein Name Matrix Metalloproteinase-17
Mmp-17
Membrane-Type Matrix Metalloproteinase 4
Mt-Mmp 4
Mtmmp4
Membrane-Type-4 Matrix Metalloproteinase
Mt4-Mmp
Mt4mmp
Database Links Reactome: R-HSA-1592389
Cellular Localisation Isoform Long: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Extracellular Side
Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Matrix Metalloproteinase-17 antibody
Anti-Mmp-17 antibody
Anti-Membrane-Type Matrix Metalloproteinase 4 antibody
Anti-Mt-Mmp 4 antibody
Anti-Mtmmp4 antibody
Anti-Membrane-Type-4 Matrix Metalloproteinase antibody
Anti-Mt4-Mmp antibody
Anti-Mt4mmp antibody
Anti-MMP17 antibody
Anti-MT4MMP antibody

Information sourced from Uniprot.org

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