Anti-Recombinant-MMP17 antibody [RM2K90] (STJA0025955)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Matrix Metalloproteinase-17 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2K90 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | MMP17 |
| Gene ID | 4326 |
| Uniprot ID | MMP17_HUMAN |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
| Protein Name | Matrix Metalloproteinase-17Mmp-17Membrane-Type Matrix Metalloproteinase 4Mt-Mmp 4Mtmmp4Membrane-Type-4 Matrix MetalloproteinaseMt4-MmpMt4mmp |
| Database Links | Reactome: R-HSA-1592389 |
| Cellular Localisation | Isoform Long: Cell MembraneLipid-AnchorGpi-AnchorExtracellular SideSecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-17 antibodyAnti-Mmp-17 antibodyAnti-Membrane-Type Matrix Metalloproteinase 4 antibodyAnti-Mt-Mmp 4 antibodyAnti-Mtmmp4 antibodyAnti-Membrane-Type-4 Matrix Metalloproteinase antibodyAnti-Mt4-Mmp antibodyAnti-Mt4mmp antibodyAnti-MMP17 antibodyAnti-MT4MMP antibody |
Information sourced from Uniprot.org