Anti-Recombinant-MAGEC2 antibody [RM2M65] (STJA0026128)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Melanoma-Associated antigen C2 for use in IHC, IP and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2M65 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | MAGEC2 |
| Gene ID | 51438 |
| Uniprot ID | MAGC2_HUMAN |
Additional Info
| Function | Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. |
| Protein Name | Melanoma-Associated Antigen C2Cancer/Testis Antigen 10Ct10Hepatocellular Carcinoma-Associated Antigen 587Mage-C2 AntigenMage-E1 Antigen |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusNuclear In Germ CellsCytoplasmic In Well-Differentiated Hepatocellular CarcinomaNuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma |
| Alternative Antibody Names | Anti-Melanoma-Associated Antigen C2 antibodyAnti-Cancer/Testis Antigen 10 antibodyAnti-Ct10 antibodyAnti-Hepatocellular Carcinoma-Associated Antigen 587 antibodyAnti-Mage-C2 Antigen antibodyAnti-Mage-E1 Antigen antibodyAnti-MAGEC2 antibodyAnti-HCA587 antibodyAnti-MAGEE1 antibody |
Information sourced from Uniprot.org