Anti-Recombinant-MAGEC2 antibody [RM2M65] (STJA0026128)

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STJA0026128
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Short Description :Rabbit monoclonal anti-Recombinant-Melanoma-Associated antigen C2 for use in IHC, IP and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IP/WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM2M65
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Formulation:0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:MAGEC2
Gene ID:51438
Uniprot ID:MAGC2_HUMAN
Function Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Protein Name Melanoma-Associated Antigen C2
Cancer/Testis Antigen 10
Ct10
Hepatocellular Carcinoma-Associated Antigen 587
Mage-C2 Antigen
Mage-E1 Antigen
Database Links
Cellular Localisation Cytoplasm
Nucleus
Nuclear In Germ Cells
Cytoplasmic In Well-Differentiated Hepatocellular Carcinoma
Nuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma
Alternative Antibody Names Anti-Melanoma-Associated Antigen C2 antibody
Anti-Cancer/Testis Antigen 10 antibody
Anti-Ct10 antibody
Anti-Hepatocellular Carcinoma-Associated Antigen 587 antibody
Anti-Mage-C2 Antigen antibody
Anti-Mage-E1 Antigen antibody
Anti-MAGEC2 antibody
Anti-HCA587 antibody
Anti-MAGEE1 antibody

Information sourced from Uniprot.org

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