Anti-Recombinant-ALKBH4 antibody [RM2M97] (STJA0026160)

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STJA0026160
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4 is suitable for use in Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2M97
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IP: 1:20, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ALKBH4
Gene ID: 54784
Uniprot ID: ALKB4_HUMAN
Function Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA, thereby regulating Polycomb silencing.
Protein Name Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4
Alkylated Dna Repair Protein Alkb Homolog 4
Dna N6-Methyl Adenine Demethylase Alkbh4
Lysine-Specific Demethylase Alkbh4
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Midbody
Associates With The Contractile Ring And Midbody
Alternative Antibody Names Anti-Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4 antibody
Anti-Alkylated Dna Repair Protein Alkb Homolog 4 antibody
Anti-Dna N6-Methyl Adenine Demethylase Alkbh4 antibody
Anti-Lysine-Specific Demethylase Alkbh4 antibody
Anti-ALKBH4 antibody
Anti-ABH4 antibody

Information sourced from Uniprot.org

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