Anti-RDH12 antibody (STJA0009236)

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STJA0009236
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Short Description :Rabbit polyclonal anti-Retinol dehydrogenase 12 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:RDH12
Gene ID:145226
Uniprot ID:RDH12_HUMAN
Immunogen:Synthesized peptide derived from human RDH12
Specificity:This antibody detects endogenous levels of RDH12 at Human, Mouse
Function Retinoids dehydrogenase/reductase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol. Also exhibits activity, albeit with lower affinity than for retinaldehydes, towards lipid peroxidation products (C9 aldehydes) such as 4-hydroxynonenal and trans-2-nonenal. May play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation. Has no dehydrogenase activity towards steroids.
Protein Name Retinol Dehydrogenase 12
All-Trans And 9-Cis Retinol Dehydrogenase
Short Chain Dehydrogenase/Reductase Family 7c Member 2
Database Links Reactome: R-HSA-2453902
Reactome: R-HSA-9918440
Cellular Localisation Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Retinol Dehydrogenase 12 antibody
Anti-All-Trans And 9-Cis Retinol Dehydrogenase antibody
Anti-Short Chain Dehydrogenase/Reductase Family 7c Member 2 antibody
Anti-RDH12 antibody
Anti-SDR7C2 antibody

Information sourced from Uniprot.org

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