| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Retinol dehydrogenase 12 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RDH12 |
| Gene ID: |
145226 |
| Uniprot ID: |
RDH12_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RDH12 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human RDH12 |
| Function | Retinoids dehydrogenase/reductase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol. Also exhibits activity, albeit with lower affinity than for retinaldehydes, towards lipid peroxidation products (C9 aldehydes) such as 4-hydroxynonenal and trans-2-nonenal. May play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation. Has no dehydrogenase activity towards steroids. |
| Protein Name | Retinol Dehydrogenase 12All-Trans And 9-Cis Retinol DehydrogenaseShort Chain Dehydrogenase/Reductase Family 7c Member 2 |
| Database Links | Reactome: R-HSA-2453864Reactome: R-HSA-2453902 |
| Cellular Localisation | Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Retinol Dehydrogenase 12 antibodyAnti-All-Trans And 9-Cis Retinol Dehydrogenase antibodyAnti-Short Chain Dehydrogenase/Reductase Family 7c Member 2 antibodyAnti-RDH12 antibodyAnti-SDR7C2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
