• Immunostaining of mouse retinal ganglion cells showing specific immunolabeling of RBPMS (1:1000) in red. Photo courtesy of Allen Rodriguez, University of California, Los Angeles.
  • Immunostaining of cat retina showing specific immunolabeling of RBPMS. Photo courtesy of Emily Brinker, Auburn University.
  • Western blot of rat heart lysate showing specific labeling of the ~24 kDa RBPMS protein.
  • Whole mount whale retina labelled with RBPMS (red) to label RGCs. Image from publication CC-BY-4. 0. PMID: 35185483

Anti-RBPMS antibody (N-Term) (STJA0003764)

SKU:
STJA0003764-100

£442.50
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Host: Rabbit
Applications: WB/IHC/ICC
Reactivity: Feline/Guinea Pig/Pig/Human/Mouse/Non-Human Primates/Rabbit/Rat/Tree Shrew/Whale/Zebrafish/Canine/Hamster
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RBPMS (N-Term) is suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 ul in PBS + 0.03% Sodium Azide
Purification: This antibody was antigen affinity purified from serum.
Dilution Range: WB 1:1000
IHC 1:100-1:2000
ICC 1:200-1:500
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Rbpms
Gene ID: 19663
Uniprot ID: RBPMS_MOUSE
Immunogen Region: N-Term
Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
Tissue Specificity mRNA expressed in developing heart, with significantly higher expression in the atria relative to the ventricles.
Function Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
Protein Name Rna-Binding Protein With Multiple Splicing
Rbp-Ms
Heart And Rrm Expressed Sequence
Hermes
Cellular Localisation Nucleus
Cytoplasm
P-Body
Translocates Into Cytoplasmic Stress Granules That Probably Correspond To P-Bodies In Response To Oxidative Stress
Alternative Antibody Names Anti-Rna-Binding Protein With Multiple Splicing antibody
Anti-Rbp-Ms antibody
Anti-Heart And Rrm Expressed Sequence antibody
Anti-Hermes antibody
Anti-Rbpms antibody
Anti-Hermes antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance