Anti-RBM38 antibody (STJA0004759)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human RBM38
General Information
| Short Description | Rabbit polyclonal anti-Rna-Binding Protein 38 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.7 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:300 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | RBM38 |
| Gene ID | 55544 |
| Uniprot ID | RBM38_HUMAN |
| Immunogen | Synthetic peptide of human RBM38 |
Additional Info
| Function | RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. (Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication. |
| Protein Name | Rna-Binding Protein 38Cll-Associated Antigen Kw-5HsrnasebRna-Binding Motif Protein 38Rna-Binding Region-Containing Protein 1Ssdna-Binding Protein Seb4 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein 38 antibodyAnti-Cll-Associated Antigen Kw-5 antibodyAnti-Hsrnaseb antibodyAnti-Rna-Binding Motif Protein 38 antibodyAnti-Rna-Binding Region-Containing Protein 1 antibodyAnti-Ssdna-Binding Protein Seb4 antibodyAnti-RBM38 antibodyAnti-RNPC1 antibodyAnti-SEB4 antibody |
Information sourced from Uniprot.org