| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Rna-Binding Protein 38 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification: |
Affinity purification |
| Concentration: |
1.7 mg/mL |
| Dilution Range: |
IHC 1:50-1:300 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Function | RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. (Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication. |
| Protein Name | Rna-Binding Protein 38Cll-Associated Antigen Kw-5HsrnasebRna-Binding Motif Protein 38Rna-Binding Region-Containing Protein 1Ssdna-Binding Protein Seb4 |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein 38 antibodyAnti-Cll-Associated Antigen Kw-5 antibodyAnti-Hsrnaseb antibodyAnti-Rna-Binding Motif Protein 38 antibodyAnti-Rna-Binding Region-Containing Protein 1 antibodyAnti-Ssdna-Binding Protein Seb4 antibodyAnti-RBM38 antibodyAnti-RNPC1 antibodyAnti-SEB4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
