Anti-Ras-G12D Mutant antibody (STJA0033656)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1/IgG2a/IgG2b
ImmunogenA synthetic peptide from the internal region of Ras which includes the mutation of G12D, human origin
General Information
| Short Description | Mouse monoclonal anti-Ras-G12D Mutant for use in WB, IHC-P, ICC, IF and ELISA in Vertebrates samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/ELISA |
| Host | Mouse |
| Reactivity | Vertebrates |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG1/IgG2a/IgG2b |
| Conjugation | Unconjugated |
| Purification | Purified from ascites |
| Dilution Range | WB-1:100-1:1000ICC/IF-1:50-1:100IHC-P-1:50-1:100ELISA-1:100-1:3000 |
| Formulation | Liquid in PBS (without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Immunogen | A synthetic peptide from the internal region of Ras which includes the mutation of G12D, human origin |
Additional Info
| Background | Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in decreased GTPase activity and constitutive signaling. This mutation is found in many types of human cancers. |
Information sourced from Uniprot.org