| Tissue Specificity | Isoform RMO1-RAPH1 is ubiquitously expressed with highest levels in brain, heart, ovary and developing embryo. Isoform RMO1 is widely expressed with highest levels in liver. Low expression in B-cells. |
| Function | Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion. |
| Protein Name | Ras-Associated And Pleckstrin Homology Domains-Containing Protein 1Raph1Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 18 ProteinAmyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 9 ProteinLamellipodinProline-Rich Evh1 Ligand 2Prel-2Protein Rmo1 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionLamellipodiumFilopodiumCytoplasmCytoskeletonRecruited To The MembraneVia The Ph DomainBy The PhosphoinositidePi(34)P2Colocalizes With Enah/Vasp At The Tips Of Lamellipodia And FilopodiaAlso Colocalizes With The PathogensVaccinia And Enteropathogenic EColi (Epec) At The Interface Between The Pathogen And Their Actin |
| Alternative Antibody Names | Anti-Ras-Associated And Pleckstrin Homology Domains-Containing Protein 1 antibodyAnti-Raph1 antibodyAnti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 18 Protein antibodyAnti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 9 Protein antibodyAnti-Lamellipodin antibodyAnti-Proline-Rich Evh1 Ligand 2 antibodyAnti-Prel-2 antibodyAnti-Protein Rmo1 antibodyAnti-RAPH1 antibodyAnti-ALS2CR18 antibodyAnti-ALS2CR9 antibodyAnti-KIAA1681 antibodyAnti-LPD antibodyAnti-PREL2 antibodyAnti-RMO1 antibody |
Information sourced from Uniprot.org
