Anti-RAPGEF4 antibody (240-320 aa) (STJ191252)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 240-320
General Information
| Short Description | Rabbit polyclonal anti-Rap guanine nucleotide exchange factor 4 (240-320 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAPGEF4 |
| Gene ID | 11069 |
| Uniprot ID | RPGF4_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 240-320 |
| Immunogen Region | 240-320 aa |
| Specificity | RPGF4 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2. |
| Protein Name | Rap Guanine Nucleotide Exchange Factor 4Exchange Factor Directly Activated By Camp 2Exchange Protein Directly Activated By Camp 2Epac 2Camp-Regulated Guanine Nucleotide Exchange Factor IiCamp-Gefii |
| Database Links | Reactome: R-HSA-354192Reactome: R-HSA-381676Reactome: R-HSA-392517Reactome: R-HSA-422356 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rap Guanine Nucleotide Exchange Factor 4 antibodyAnti-Exchange Factor Directly Activated By Camp 2 antibodyAnti-Exchange Protein Directly Activated By Camp 2 antibodyAnti-Epac 2 antibodyAnti-Camp-Regulated Guanine Nucleotide Exchange Factor Ii antibodyAnti-Camp-Gefii antibodyAnti-RAPGEF4 antibodyAnti-CGEF2 antibodyAnti-EPAC2 antibody |
Information sourced from Uniprot.org