| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Rap guanine nucleotide exchange factor 4 (240-320 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAPGEF4 |
| Gene ID: |
11069 |
| Uniprot ID: |
RPGF4_HUMAN |
| Immunogen Region: |
240-320 aa |
| Specificity: |
RPGF4 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 240-320 |
| Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2. |
| Protein Name | Rap Guanine Nucleotide Exchange Factor 4Exchange Factor Directly Activated By Camp 2Exchange Protein Directly Activated By Camp 2Epac 2Camp-Regulated Guanine Nucleotide Exchange Factor IiCamp-Gefii |
| Database Links | Reactome: R-HSA-354192Reactome: R-HSA-381676Reactome: R-HSA-392517Reactome: R-HSA-422356 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rap Guanine Nucleotide Exchange Factor 4 antibodyAnti-Exchange Factor Directly Activated By Camp 2 antibodyAnti-Exchange Protein Directly Activated By Camp 2 antibodyAnti-Epac 2 antibodyAnti-Camp-Regulated Guanine Nucleotide Exchange Factor Ii antibodyAnti-Camp-Gefii antibodyAnti-RAPGEF4 antibodyAnti-CGEF2 antibodyAnti-EPAC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
