Anti-RAI14 antibody (300-600) (STJ118256)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RAI14 (300-600) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAI14 |
| Gene ID | 26064 |
| Uniprot ID | RAI14_HUMAN |
| Immunogen Region | 300-600 |
| Immunogen Sequence | SGKESVFFAEPPFKAEISSI RENKDRLSDSTTGADSLLDI SSEADQQDLLSLLQAKVASL TLHNKELQDKLQAKSPKEAE ADLSFDSYHSTQTDLGPSLG KPGETSPPDSKSSPSVLIHS LGKSTTDNDVRIQQLQEILQ DLQKRLESSEAERKQLQVEL QSRRAELVCLNNTEISENSS DLSQKLKETQSKYEEAMKEV LSVQKQMKLGLVSPESMDNY SHFHELRVTEEEINVLKQD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human RAI14 (NP_056392.2). |
Additional Info
| Tissue Specificity | Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa. |
| Function | Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier. |
| Protein Name | AnkycorbinAnkyrin Repeat And Coiled-Coil Structure-Containing ProteinNovel Retinal Pigment Epithelial Cell ProteinRetinoic Acid-Induced Protein 14 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberCell CortexCell JunctionNucleusAssociated With The Cortical Actin Cytoskeleton Structures In Terminal Web And Cell-Cell Adhesion SitesHighly Expressed At The Ectoplasmic SpecializationAn Actin-Rich Cell Junction Specific To The TestisPredominantly Nuclear In Nonconfluent Cells |
| Alternative Antibody Names | Anti-Ankycorbin antibodyAnti-Ankyrin Repeat And Coiled-Coil Structure-Containing Protein antibodyAnti-Novel Retinal Pigment Epithelial Cell Protein antibodyAnti-Retinoic Acid-Induced Protein 14 antibodyAnti-RAI14 antibodyAnti-KIAA1334 antibodyAnti-NORPEG antibody |
Information sourced from Uniprot.org