| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAI14 (300-600) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAI14 |
| Gene ID: |
26064 |
| Uniprot ID: |
RAI14_HUMAN |
| Immunogen Region: |
300-600 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human RAI14 (NP_056392.2). |
| Immunogen Sequence: |
SGKESVFFAEPPFKAEISSI RENKDRLSDSTTGADSLLDI SSEADQQDLLSLLQAKVASL TLHNKELQDKLQAKSPKEAE ADLSFDSYHSTQTDLGPSLG KPGETSPPDSKSSPSVLIHS LGKSTTDNDVRIQQLQEILQ DLQKRLESSEAERKQLQVEL QSRRAELVCLNNTEISENSS DLSQKLKETQSKYEEAMKEV LSVQKQMKLGLVSPESMDNY SHFHELRVTEEEINVLKQD |
| Tissue Specificity | Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa. |
| Function | Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier. |
| Protein Name | AnkycorbinAnkyrin Repeat And Coiled-Coil Structure-Containing ProteinNovel Retinal Pigment Epithelial Cell ProteinRetinoic Acid-Induced Protein 14 |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberCell CortexCell JunctionNucleusAssociated With The Cortical Actin Cytoskeleton Structures In Terminal Web And Cell-Cell Adhesion SitesHighly Expressed At The Ectoplasmic SpecializationAn Actin-Rich Cell Junction Specific To The TestisPredominantly Nuclear In Nonconfluent Cells |
| Alternative Antibody Names | Anti-Ankycorbin antibodyAnti-Ankyrin Repeat And Coiled-Coil Structure-Containing Protein antibodyAnti-Novel Retinal Pigment Epithelial Cell Protein antibodyAnti-Retinoic Acid-Induced Protein 14 antibodyAnti-RAI14 antibodyAnti-KIAA1334 antibodyAnti-NORPEG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
