Anti-RAD52 antibody (319-418) [S7MR] (STJ11102287)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Rad52 (319-418) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAD52 |
| Gene ID | 5893 |
| Uniprot ID | RAD52_HUMAN |
| Immunogen Region | 319-418 |
| Immunogen Sequence | QELIKTLEDNSEKWAVTPDA GDGVVKPSSRADPAQTSDTL ALNNQMVTQNRTPHSVCHQK PQAKSGSWDLQTYSADQRTT GNWESHRKSQDMKKRKYDPS |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 319-418 of human Rad52 (P43351). |
Additional Info
| Post Translational Modifications | Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR. |
| Function | Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. |
| Protein Name | Dna Repair Protein Rad52 Homolog |
| Database Links | Reactome: R-HSA-3108214Reactome: R-HSA-5685938Reactome: R-HSA-5685939 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Repair Protein Rad52 Homolog antibodyAnti-RAD52 antibody |
Information sourced from Uniprot.org