• STJ70120 (0. 1µg/ml) staining of Human Thymus (A) and Tonsil (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • STJ70120 (0. 3µg/ml) staining of MOLT4 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-RAC2 antibody (C-Term) (STJ70120)

SKU:
STJ70120-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-RAC2 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.1-0.3µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: RAC2
Gene ID: 5880
Uniprot ID: RAC2_HUMAN
Immunogen Region: C-Term
Accession Number: NP_002863.1
Immunogen Sequence: PQPTRQQKRACSLL
Post Translational Modifications (Microbial infection) Glycosylated at Tyr-32 by Photorhabdus asymbiotica toxin PAU_02230. Mono-O-GlcNAcylation by PAU_02230 inhibits downstream signaling by an impaired interaction with diverse regulator and effector proteins of Rac and leads to actin disassembly.
Function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Protein Name Ras-Related C3 Botulinum Toxin Substrate 2
Gx
Small G Protein
P21-Rac2
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1222556
Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-4086400
Reactome: R-HSA-5668599
Reactome: R-HSA-6811558
Reactome: R-HSA-9013404
Cellular Localisation Cytoplasm
Membrane-Associated When Activated
Alternative Antibody Names Anti-Ras-Related C3 Botulinum Toxin Substrate 2 antibody
Anti-Gx antibody
Anti-Small G Protein antibody
Anti-P21-Rac2 antibody
Anti-RAC2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance